ADRB2

GENE INFORMATION

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Gene name

ADRB2 (HGNC Symbol)

Synonyms

ADRB2R, ADRBR, B2AR, BAR

Description

adrenoceptor beta 2, surface (HGNC Symbol)

Entrez gene summary

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q32

Chromosome location (bp)

148206156 - 148208196

Ensembl

ENSG00000169252 (version 73.37)

Entrez gene

154

UniProt

P07550 (UniProt - Evidence at protein level)

neXtProt

NX_P07550

Antibodypedia

ADRB2 antibodies
 

PROTEIN VIEW

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ADRB2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADRB2-001 ENSP00000305372
ENST00000305988
P07550
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