B3GALNT1

GENE INFORMATION

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Gene name

B3GALNT1 (HGNC Symbol)

Synonyms

B3GALT3, beta3Gal-T3, galT3, GLOB, P1

Description

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) (HGNC Symbol)

Entrez gene summary

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q26.1

Chromosome location (bp)

160801671 - 160823172

Ensembl

ENSG00000169255 (version 73.37)

Entrez gene

8706

UniProt

O75752 (UniProt - Evidence at transcript level)

neXtProt

NX_O75752

Antibodypedia

B3GALNT1 antibodies
 

PROTEIN VIEW

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 « 
 
B3GALNT1-001
 
B3GALNT1-002
 
B3GALNT1-003
 
B3GALNT1-004
 
B3GALNT1-005
 
B3GALNT1-006
 
B3GALNT1-007
 
B3GALNT1-010
 
B3GALNT1-012
 
B3GALNT1-013
 
B3GALNT1-014
 
B3GALNT1-015
 
B3GALNT1-016
 
B3GALNT1-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

B3GALNT1-001 ENSP00000376530
ENST00000392779
O75752
Show all »
Show » Show » 331 39.5 No 0
B3GALNT1-002 ENSP00000323479
ENST00000320474
O75752
Show all »
Show » Show » 331 39.5 No 0
B3GALNT1-003 ENSP00000376532
ENST00000392781
O75752
Show all »
Show » Show » 331 39.5 No 0
B3GALNT1-004 ENSP00000420163
ENST00000488170
O75752
Show all »
Show » Show » 331 39.5 No 0
B3GALNT1-005 ENSP00000418226
ENST00000473285
O75752
Show all »
Show » Show » 331 39.5 No 0
B3GALNT1-006 ENSP00000407027
ENST00000417187
E7EVF0
Show all »
Show » Show » 91 11 No 0
B3GALNT1-007 ENSP00000419127
ENST00000494173
C9JXR0
Show all »
Show » 29 3.3 Yes 0
B3GALNT1-010 ENSP00000420059
ENST00000484127
C9JRV6
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Show » Show » 41 4.9 No 0
B3GALNT1-012 ENSP00000417643
ENST00000498216
C9J8U7
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Show » Show » 54 6.6 No 0
B3GALNT1-013 ENSP00000419476
ENST00000468268
E7EVS2
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Show » Show » 111 13.5 No 0
B3GALNT1-014 ENSP00000417053
ENST00000460353
C9J6I7
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Show » Show » 150 17.1 No 0
B3GALNT1-015 ENSP00000420604
ENST00000473142
C9JD16
Show all »
Show » Show » 58 7.1 No 0
B3GALNT1-016 ENSP00000418567
ENST00000492353
C9J0F8
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Show » Show » 65 8.1 No 0
B3GALNT1-201 ENSP00000376531
ENST00000392780
O75752
Show all »
Show » Show » 331 39.5 No 0