KCNAB1

GENE INFORMATION

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Gene name

KCNAB1 (HGNC Symbol)

Synonyms

AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3

Description

potassium voltage-gated channel, shaker-related subfamily, beta member 1 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q25.31

Chromosome location (bp)

155755490 - 156256545

Ensembl

ENSG00000169282 (version 73.37)

Entrez gene

7881

UniProt

Q14722 (UniProt - Evidence at transcript level)

neXtProt

NX_Q14722

Antibodypedia

KCNAB1 antibodies
 

PROTEIN VIEW

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KCNAB1-001
 
KCNAB1-002
 
KCNAB1-003
 
KCNAB1-004
 
KCNAB1-006
 
KCNAB1-009
 
KCNAB1-010
 
KCNAB1-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNAB1-001 ENSP00000305858
ENST00000302490
Q14722
Show all »
Show » Show » 401 44.7 No 0
KCNAB1-002 ENSP00000419952
ENST00000490337
Q14722
Show all »
Show » Show » 419 46.6 No 0
KCNAB1-003 ENSP00000374287
ENST00000389636
B7Z8E5
Show all »
Show » 390 43.3 No 0
KCNAB1-004 ENSP00000418956
ENST00000471742
Q14722
Show all »
Show » Show » 408 45.5 No 0
KCNAB1-006 ENSP00000374285
ENST00000389634
F8W6W4
Show all »
Show » 372 41.4 No 0
KCNAB1-009 ENSP00000420755
ENST00000472028
C9JBV8
Show all »
129 14.3 No 0
KCNAB1-010 ENSP00000420221
ENST00000475456
C9JQ60
Show all »
177 19.8 No 0
KCNAB1-011 ENSP00000418048
ENST00000489036
H7C4S9
Show all »
81 9.1 No 0