MRPL1

GENE INFORMATION

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Gene name

MRPL1 (HGNC Symbol)

Synonyms

BM022

Description

mitochondrial ribosomal protein L1 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

78783674 - 78873944

Ensembl

ENSG00000169288 (version 73.37)

Entrez gene

65008

UniProt

Q9BYD6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYD6

Antibodypedia

MRPL1 antibodies
 

PROTEIN VIEW

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MRPL1-001
 
MRPL1-002
 
MRPL1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL1-001 ENSP00000315017
ENST00000315567
Q9BYD6
Show all »
Show » Show » 325 36.9 No 0
MRPL1-002 ENSP00000421616
ENST00000502384
Show » Show » 231 26.6 No 0
MRPL1-006 ENSP00000426575
ENST00000504901
Show » 119 13 No 0