P2RY12

GENE INFORMATION

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Gene name

P2RY12 (HGNC Symbol)

Synonyms

HORK3, P2Y12, SP1999

Description

purinergic receptor P2Y, G-protein coupled, 12 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Chromosome

3 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

151055168 - 151102600

Ensembl

ENSG00000169313 (version 73.37)

Entrez gene

64805

UniProt

Q9H244 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H244

Antibodypedia

P2RY12 antibodies
 

PROTEIN VIEW

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P2RY12-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

P2RY12-001 ENSP00000307259
ENST00000302632
Q9H244
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