PTK2

GENE INFORMATION

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Gene name

PTK2 (HGNC Symbol)

Synonyms

FADK, FAK, FAK1, PPP1R71

Description

protein tyrosine kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]

Chromosome

8 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

141667999 - 142012315

Ensembl

ENSG00000169398 (version 73.37)

Entrez gene

5747

UniProt

Q05397 (UniProt - Evidence at protein level)

neXtProt

NX_Q05397

Antibodypedia

PTK2 antibodies
 

PROTEIN VIEW

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 « 
 
PTK2-001
 
PTK2-002
 
PTK2-003
 
PTK2-004
 
PTK2-005
 
PTK2-006
 
PTK2-007
 
PTK2-008
 
PTK2-009
 
PTK2-010
 
PTK2-011
 
PTK2-013
 
PTK2-014
 
PTK2-015
 
PTK2-019
 
PTK2-020
 
PTK2-031
 
PTK2-032
 
PTK2-033
 
PTK2-034
 
PTK2-035
 
PTK2-037
 
PTK2-038
 
PTK2-039
 
PTK2-040
 
PTK2-041
 
PTK2-042
 
PTK2-043
 
PTK2-044
 
PTK2-045
 
PTK2-046
 
PTK2-047
 
PTK2-049
 
PTK2-050
 
PTK2-051
 
PTK2-052
 
PTK2-053
 
PTK2-054
 
PTK2-055
 
PTK2-057
 
PTK2-201
 
PTK2-202
 
PTK2-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTK2-001 ENSP00000429911
ENST00000522684
Q05397
Show all »
Show » Show » 1052 119.2 No 0
PTK2-002 ENSP00000428492
ENST00000523539
H0YB16
Show all »
Show » 724 81.5 No 0
PTK2-003 ENSP00000429023
ENST00000524202
Show » 319 35.8 No 0
PTK2-004 ENSP00000430916
ENST00000517712
E5RHD8
Show all »
Show » 115 12.9 No 0
PTK2-005 ENSP00000429170
ENST00000519465
E9PEI4
Show all »
Show » 680 76.8 No 0
PTK2-006 ENSP00000403416
ENST00000430260
B4DWJ1
Show all »
Show » 362 40.2 No 0
PTK2-007 ENSP00000429129
ENST00000519419
E7ESA6
Show all »
Show » 1096 124.1 No 0
PTK2-008 ENSP00000429082
ENST00000517887
E7ESA6
Show all »
Show » 1096 124.1 No 0
PTK2-009 ENSP00000430603
ENST00000521986
H0YBZ1
Show all »
Show » 753 84.8 No 0
PTK2-010 ENSP00000429929
ENST00000519654
Q8IYN9
Show all »
Show » 1017 115.4 No 0
PTK2-011 ENSP00000341189
ENST00000340930
Q05397
Show all »
Show » Show » 1065 120.9 No 0
PTK2-013 ENSP00000428570
ENST00000519993
E5RG54
Show all »
Show » 66 7.3 No 0
PTK2-014 ENSP00000429437
ENST00000522950
E5RII9
Show all »
67 7.6 No 0
PTK2-015 ENSP00000430828
ENST00000523435
E5RI03
Show all »
Show » 120 13.7 No 0
PTK2-019 ENSP00000431106
ENST00000521562
E5RJQ2
Show all »
Show » 132 14.8 No 0
PTK2-020 ENSP00000429702
ENST00000523388
E5RHK7
Show all »
Show » 67 7.3 No 0
PTK2-031 ENSP00000427825
ENST00000521791
E5RG54
Show all »
Show » 66 7.3 No 0
PTK2-032 ENSP00000429530
ENST00000523803
E5RI72
Show all »
Show » 120 13.7 No 0
PTK2-033 ENSP00000428792
ENST00000520475
E5RGA6
Show all »
Show » 156 18.2 No 0
PTK2-034 ENSP00000429907
ENST00000521395
E5RH48
Show all »
Show » 107 12 No 0
PTK2-035 ENSP00000427795
ENST00000521907
E5RG66
Show all »
Show » 119 13.5 No 0
PTK2-037 ENSP00000430277
ENST00000519881
E5RFW9
Show all »
Show » 121 13.8 No 0
PTK2-038 ENSP00000427904
ENST00000520892
E5RFW9
Show all »
Show » 121 13.8 No 0
PTK2-039 ENSP00000429409
ENST00000521332
E5RIK4
Show all »
Show » 65 7.2 No 0
PTK2-040 ENSP00000429028
ENST00000523679
15 1.5 No 0
PTK2-041 ENSP00000427762
ENST00000520828
E5RG86
Show all »
Show » 59 7.2 No 0
PTK2-042 ENSP00000431023
ENST00000524257
8 0.9 No 0
PTK2-043 ENSP00000430951
ENST00000517453
E5RH01
Show all »
Show » 117 13.2 No 0
PTK2-044 ENSP00000430044
ENST00000520045
E5RH01
Show all »
Show » 117 13.2 No 0
PTK2-045 ENSP00000430037
ENST00000524040
E5RH08
Show all »
Show » 51 5.6 No 0
PTK2-046 ENSP00000429895
ENST00000523067
E5RG54
Show all »
Show » 66 7.3 No 0
PTK2-047 ENSP00000427774
ENST00000522424
E5RG80
Show all »
Show » 133 15 No 0
PTK2-049 ENSP00000427972
ENST00000521250
H0YAS0
Show all »
72 8 No 0
PTK2-050 ENSP00000428380
ENST00000523670
E5RIR5
Show all »
Show » 72 8.4 No 0
PTK2-051 ENSP00000429958
ENST00000521029
E5RGP1
Show all »
Show » 79 9.2 No 0
PTK2-052 ENSP00000428593
ENST00000521981
H0YB33
Show all »
Show » 128 14.3 No 0
PTK2-053 ENSP00000428232
ENST00000519024
E5RJI4
Show all »
Show » 169 19.3 No 0
PTK2-054 ENSP00000428482
ENST00000520151
E5RI29
Show all »
Show » 124 14 No 0
PTK2-055 ENSP00000429001
ENST00000524357
E5RJP0
Show all »
Show » 122 13.8 No 0
PTK2-057 ENSP00000429474
ENST00000521059
Q05397
Show all »
Show » Show » 1052 119.2 No 0
PTK2-201 ENSP00000378644
ENST00000395218
J3QT16
Show all »
Show » 1065 120.8 No 0
PTK2-202 ENSP00000438009
ENST00000535192
Q8IYN9
Show all »
Show » 1006 114.3 No 0
PTK2-203 ENSP00000445742
ENST00000538769
Q8N9D7
Show all »
Show » 720 81 No 0