IL8

GENE INFORMATION

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Gene name

IL8 (HGNC Symbol)

Synonyms

3-10C, AMCF-I, b-ENAP, CXCL8, GCP-1, GCP1, IL-8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1

Description

interleukin 8 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

74606223 - 74609433

Ensembl

ENSG00000169429 (version 73.37)

Entrez gene

3576

UniProt

P10145 (UniProt - Evidence at protein level)

neXtProt

NX_P10145

Antibodypedia

IL8 antibodies
 

PROTEIN VIEW

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IL8-001
 
IL8-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL8-001 ENSP00000306512
ENST00000307407
P10145
Show all »
Show » Show » 99 11.1 Yes 0
IL8-002 ENSP00000385908
ENST00000401931
C9J4T6
Show all »
Show » Show » 95 10.7 Yes 0