AGPAT2

GENE INFORMATION

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Gene name

AGPAT2 (HGNC Symbol)

Synonyms

BSCL

Description

1-acylglycerol-3-phosphate O-acyltransferase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q34.3

Chromosome location (bp)

139567595 - 139581875

Ensembl

ENSG00000169692 (version 73.37)

Entrez gene

10555

UniProt

O15120 (UniProt - Evidence at protein level)

neXtProt

NX_O15120

Antibodypedia

AGPAT2 antibodies
 

PROTEIN VIEW

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AGPAT2-001
 
AGPAT2-002
 
AGPAT2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGPAT2-001 ENSP00000360761
ENST00000371696
O15120
Show all »
Show » Show » 278 30.9 Yes 3
AGPAT2-002 ENSP00000360759
ENST00000371694
O15120
Show all »
Show » Show » 246 27.3 Yes 2
AGPAT2-201 ENSP00000438919
ENST00000538402
O15120
Show all »
Show » Show » 278 30.9 Yes 3