NLGN1

GENERAL INFORMATION

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Gene name

NLGN1

Gene description

Neuroligin 1

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Strong cytoplasmic positivity was observed in neuronal cells, adrenal cortical cells, chief cells of stomach, alveolar macrophages and plasma cells. Some glandular epithelia showed moderate cytoplasmic staining. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA006680
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

NLGN1 (HGNC Symbol)

Synonyms

KIAA1070

Description

Neuroligin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q26.31

Chromosome location (bp)

173396284 - 174286644

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169760 (version 78.38)

Entrez gene

22871

UniProt

Q8N2Q7 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N2Q7

Antibodypedia

NLGN1 antibodies


PROTEIN BROWSER

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ENST00000361589
 
ENST00000401917
 
ENST00000413821
 
ENST00000415045
 
ENST00000423427
 
ENST00000457714
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NLGN1-001 ENSP00000392500
ENST00000457714
Q8N2Q7
Show all »
Show » Show » 823 92 No 1
NLGN1-002 ENSP00000354541
ENST00000361589
Q8N2Q7
Show all »
Show » Show » 823 92 No 1
NLGN1-003 ENSP00000410374
ENST00000415045
C9J4D3
Show all »
Show » Show » 367 39.9 No 0
NLGN1-005 ENSP00000407255
ENST00000423427
Show » 13 1.6 No 0
NLGN1-007 ENSP00000401843
ENST00000413821
Show » 10 1.2 No 0
NLGN1-201 ENSP00000385750
ENST00000401917
Show » 608 68.3 No 1