GUSB

GENE INFORMATION

? »

Gene name

GUSB

Synonyms

Description

Glucuronidase, beta (HGNC Symbol)

Entrez gene summary

This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, Nov 2009]

Chromosome

7

Cytoband

q11.21

Chromosome location (bp)

65425671 - 65447301

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169919 (version 75.37)

Entrez gene

2990

UniProt

P08236 (UniProt - Evidence at protein level)

neXtProt

NX_P08236

Antibodypedia

GUSB antibodies
 

PROTEIN VIEW

? »
 
 
 
GUSB-001
 
GUSB-002
 
GUSB-004
 
GUSB-007
 
GUSB-008
 
GUSB-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GUSB-001 ENSP00000302728
ENST00000304895
P08236
Show all »
Show » Show » 651 74.7 Yes 0
GUSB-002 ENSP00000391390
ENST00000421103
E9PCV0
Show all »
Show » Show » 505 58.3 Yes 0
GUSB-004 ENSP00000416793
ENST00000446111
F2Z3L6
Show all »
Show » Show » 144 16.7 Yes 0
GUSB-007 ENSP00000411262
ENST00000447929
F2Z3L6
Show all »
Show » Show » 144 16.7 Yes 0
GUSB-008 ENSP00000411859
ENST00000430730
F8WBK6
Show all »
Show » Show » 134 15.6 Yes 0
GUSB-201 ENSP00000340734
ENST00000345660
P08236
Show all »
Show » Show » 600 69.1 Yes 0