MAP3K2

GENE INFORMATION

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Gene name

MAP3K2 (HGNC Symbol)

Synonyms

MEKK2, MEKK2B

Description

mitogen-activated protein kinase kinase kinase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q14.3

Chromosome location (bp)

128056306 - 128146041

Ensembl

ENSG00000169967 (version 73.37)

Entrez gene

10746

UniProt

Q9Y2U5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2U5

Antibodypedia

MAP3K2 antibodies
 

PROTEIN VIEW

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MAP3K2-001
 
MAP3K2-002
 
MAP3K2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP3K2-001 ENSP00000387246
ENST00000409947
Q9Y2U5
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Show » Show » 619 69.7 No 0
MAP3K2-002 ENSP00000343463
ENST00000344908
Q9Y2U5
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Show » Show » 619 69.7 No 0
MAP3K2-003 ENSP00000386313
ENST00000409179
F8W6K3
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47 5.3 No 0