CHD3

GENE INFORMATION

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Gene name

CHD3 (HGNC Symbol)

Synonyms

Mi-2a, Mi2-ALPHA, ZFH

Description

chromodomain helicase DNA binding protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

7788124 - 7816078

Ensembl

ENSG00000170004 (version 73.37)

Entrez gene

1107

UniProt

Q12873 (UniProt - Evidence at protein level)

neXtProt

NX_Q12873

Antibodypedia

CHD3 antibodies
 

PROTEIN VIEW

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CHD3-001
 
CHD3-002
 
CHD3-003
 
CHD3-004
 
CHD3-006
 
CHD3-010
 
CHD3-011
 
CHD3-015
 
CHD3-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHD3-001 ENSP00000332628
ENST00000330494
Q12873
Show all »
Show » Show » 2000 226.6 No 0
CHD3-002 ENSP00000350907
ENST00000358181
Q12873
Show all »
Show » Show » 1966 222.9 No 0
CHD3-003 ENSP00000369716
ENST00000380358
Q12873
Show all »
Show » Show » 2059 233 No 0
CHD3-004 ENSP00000467547
ENST00000470531
K7EPV1
Show all »
63 7.8 No 0
CHD3-006 ENSP00000405861
ENST00000452447
Show » 525 58.8 No 0
CHD3-010 ENSP00000395252
ENST00000439235
H7C0J3
Show all »
Show » 383 41.8 No 0
CHD3-011 ENSP00000411959
ENST00000449744
H7C3H7
Show all »
Show » 277 30.5 No 0
CHD3-015 ENSP00000458861
ENST00000571249
110 11.9 No 0
CHD3-016 ENSP00000459321
ENST00000573936
I3L229
Show all »
Show » 250 27.9 No 0