CHRNB1

GENE INFORMATION

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Gene name

CHRNB1 (HGNC Symbol)

Synonyms

CHRNB

Description

cholinergic receptor, nicotinic, beta 1 (muscle) (HGNC Symbol)

Entrez gene summary

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

7348380 - 7361026

Ensembl

ENSG00000170175 (version 73.37)

Entrez gene

1140

UniProt

P11230 (UniProt - Evidence at protein level)

neXtProt

NX_P11230

Antibodypedia

CHRNB1 antibodies
 

PROTEIN VIEW

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CHRNB1-001
 
CHRNB1-002
 
CHRNB1-004
 
CHRNB1-006
 
CHRNB1-007
 
CHRNB1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRNB1-001 ENSP00000304290
ENST00000306071
P11230
Show all »
Show » Show » 501 56.7 Yes 4
CHRNB1-002 ENSP00000439209
ENST00000536404
B7Z5H1
Show all »
Show » Show » 429 49.1 No 4
CHRNB1-004 ENSP00000461402
ENST00000572857
I3L4N5
Show all »
Show » Show » 158 16.8 Yes 0
CHRNB1-006 ENSP00000459092
ENST00000576360
I3L1T7
Show all »
Show » Show » 380 43.7 No 2
CHRNB1-007 ENSP00000460648
ENST00000570557
Show » Show » 316 35.7 No 2
CHRNB1-008 ENSP00000461751
ENST00000575379
I3L535
Show all »
Show » Show » 37 4.3 No 1