GYPA

GENE INFORMATION

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Gene name

GYPA (HGNC Symbol)

Synonyms

CD235a, GPA, MN, MNS

Description

glycophorin A (MNS blood group) (HGNC Symbol)

Entrez gene summary

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q31.21

Chromosome location (bp)

145030457 - 145061904

Ensembl

ENSG00000170180 (version 73.37)

Entrez gene

2993

UniProt

P02724 (UniProt - Evidence at protein level)

neXtProt

NX_P02724

Antibodypedia

GYPA antibodies
 

PROTEIN VIEW

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GYPA-001
 
GYPA-002
 
GYPA-003
 
GYPA-004
 
GYPA-005
 
GYPA-006
 
GYPA-007
 
GYPA-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GYPA-001 ENSP00000354003
ENST00000360771
P02724
Show all »
Show » Show » 150 16.4 Yes 1
GYPA-002 ENSP00000324483
ENST00000324022
B8Q185
Show all »
Show » Show » 117 13 No 1
GYPA-003 ENSP00000425719
ENST00000508337
D6RJD8
Show all »
42 4.6 Yes 0
GYPA-004 ENSP00000425193
ENST00000512789
Q13030
Show all »
Show » Show » 85 9.3 Yes 1
GYPA-005 ENSP00000425549
ENST00000504786
E7EQF3
Show all »
Show » Show » 118 12.8 Yes 1
GYPA-006 ENSP00000421243
ENST00000503627
E9PH25
Show all »
Show » Show » 105 11.3 Yes 1
GYPA-007 ENSP00000426130
ENST00000512064
E9PD10
Show all »
Show » Show » 137 14.9 Yes 1
GYPA-201 ENSP00000445398
ENST00000535709
B8Q182
Show all »
Show » Show » 124 13.6 No 1