PFKFB3

GENERAL INFORMATION

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Gene name

PFKFB3

Gene description

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a majority of tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA008266 , CAB020795
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PFKFB3

Synonyms

Description

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (HGNC Symbol)

Entrez gene summary

Chromosome

10

Cytoband

p15.1

Chromosome location (bp)

6144934 - 6235545

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170525 (version 78.38)

Entrez gene

5209

UniProt

Q16875 (UniProt - Evidence at protein level)

neXtProt

NX_Q16875

Antibodypedia

PFKFB3 antibodies


PROTEIN BROWSER

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ENST00000317350
 
ENST00000360521
 
ENST00000379775
 
ENST00000379785
 
ENST00000379789
 
ENST00000414237
 
ENST00000441697
 
ENST00000450232
 
ENST00000536985
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PFKFB3-001 ENSP00000369115
ENST00000379789
Q16875
Show all »
Show » Show » 500 57.3 No 0
PFKFB3-002 ENSP00000369100
ENST00000379775
Q16875
Show all »
Show » Show » 520 59.6 No 0
PFKFB3-005 ENSP00000416677
ENST00000414237
Q9H178
Show all »
Show » Show » 92 10 No 0
PFKFB3-006 ENSP00000353712
ENST00000360521
Q16875
Show all »
Show » Show » 514 58.9 No 0
PFKFB3-010 ENSP00000369111
ENST00000379785
Q5VX20
Show all »
Show » Show » 526 60.3 No 0
PFKFB3-011 ENSP00000404995
ENST00000441697
Q9BQU1
Show all »
Show » Show » 31 3.6 No 0
PFKFB3-013 ENSP00000390285
ENST00000450232
Q9BQU1
Show all »
Show » Show » 143 16.5 No 0
PFKFB3-015 ENSP00000369105
ENST00000317350
Q5W015
Show all »
Show » Show » 513 58.8 No 0
PFKFB3-201 ENSP00000443319
ENST00000536985
Q16875
Show all »
Show » Show » 534 60.6 No 0