The chromosomal and cytoband location of the gene according to Ensembl is reported together with the Ensembl gene identifier and Ensembl database version.
The Entrez gene identifier for the gene is also given. If any of the protein products of
the gene is linked to a UniProt KB/SWISS-PROT entry, links to the UniProt and the
neXtProt databases for these proteins are displayed.
There is also a link to the Antibodypedia portal where validation data for antibodies produced by other suppliers
against this gene can be found.
TRIAP1 (HGNC Symbol)
HSPC132, MDM35, P53CSV, WF-1
TP53 regulated inhibitor of apoptosis 1 (HGNC Symbol)
The protein view displays protein features. The tabs at the top of the protein view section can be used to switch between the different splice variants encoded by this gene. The mouse over function displays additional data for the features in the protein view.
At the top of the protein view, the maximum percent sequence identity of the protein to all other proteins from other human genes is shown, using a sliding window of 10 aa residues
(HsID 10) or 50 aa residues (HsID 50) (read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS,
SignalP 4.0, and
(turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
The protein information section displays the alternative protein-coding transcripts (splice variants) encoded by this gene, according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant.
The data in the UniProt column can be expanded to show links to all matching
UniProt identifiers for this protein.
The protein classes to which this protein has been assigned are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors
SignalP 4.0, and
Phobius) and the number of predicted transmembrane region(s) (according to
MDM) are also reported.
GO:0002039 [p53 binding] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005758 [mitochondrial intermembrane space] GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest] GO:0015914 [phospholipid transport] GO:0030330 [DNA damage response, signal transduction by p53 class mediator] GO:0034644 [cellular response to UV] GO:0043066 [negative regulation of apoptotic process] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0043234 [protein complex] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0090201 [negative regulation of release of cytochrome c from mitochondria] GO:0097035 [regulation of membrane lipid distribution] GO:1902166 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] GO:1990050 [phosphatidic acid transporter activity] GO:2001140 [positive regulation of phospholipid transport]
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.