S1PR1

GENE INFORMATION

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Gene name

S1PR1 (HGNC Symbol)

Synonyms

CD363, D1S3362, edg-1, EDG1

Description

sphingosine-1-phosphate receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p21.2

Chromosome location (bp)

101702444 - 101707074

Ensembl

ENSG00000170989 (version 73.37)

Entrez gene

1901

UniProt

P21453 (UniProt - Evidence at protein level)

neXtProt

NX_P21453

Antibodypedia

S1PR1 antibodies
 

PROTEIN VIEW

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S1PR1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

S1PR1-001 ENSP00000305416
ENST00000305352
P21453
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