CCBL1

GENERAL INFORMATION

? »

Gene name

CCBL1

Gene description

Cysteine conjugate-beta lyase, cytoplasmic

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA021176 , HPA021177 , HPA027736
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

CCBL1 (HGNC Symbol)

Synonyms

GTK, KATI

Description

Cysteine conjugate-beta lyase, cytoplasmic (HGNC Symbol)

Entrez gene summary

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q34.11

Chromosome location (bp)

128832942 - 128882494

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171097 (version 78.38)

Entrez gene

883

UniProt

Q16773 (UniProt - Evidence at protein level)

neXtProt

NX_Q16773

Antibodypedia

CCBL1 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000302586
 
ENST00000320665
 
ENST00000416084
 
ENST00000427720
 
ENST00000436267
 
ENST00000451800
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCBL1-001 ENSP00000302227
ENST00000302586
Q16773
Show all »
Show » Show » 422 47.9 No 0
CCBL1-002 ENSP00000317342
ENST00000320665
Q16773
Show all »
Show » Show » 372 42.5 No 0
CCBL1-005 ENSP00000390377
ENST00000451800
Q5T278
Show all »
Show » Show » 251 27.8 No 0
CCBL1-007 ENSP00000412402
ENST00000416084
Q5T276
Show all »
Show » Show » 184 20.3 No 0
CCBL1-009 ENSP00000392354
ENST00000427720
Q5T277
Show all »
Show » 159 17.5 No 0
CCBL1-201 ENSP00000399415
ENST00000436267
B7Z4W5
Show all »
Show » Show » 516 57.7 No 0