INSR

GENE INFORMATION

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Gene name

INSR (HGNC Symbol)

Synonyms

CD220

Description

insulin receptor (HGNC Symbol)

Entrez gene summary

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

7112266 - 7294045

Ensembl

ENSG00000171105 (version 73.37)

Entrez gene

3643

UniProt

P06213 (UniProt - Evidence at protein level)

neXtProt

NX_P06213

Antibodypedia

INSR antibodies
 

PROTEIN VIEW

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INSR-001
 
INSR-002
 
INSR-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

INSR-001 ENSP00000303830
ENST00000302850
P06213
Show all »
Show » Show » 1382 156.3 Yes 1
INSR-002 ENSP00000342838
ENST00000341500
P06213
Show all »
Show » Show » 1370 155.1 Yes 1
INSR-004 ENSP00000473170
ENST00000600492
M0R3E6
Show all »
Show » 152 17.2 No 0