KCNMB3

GENE INFORMATION

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Gene name

KCNMB3 (HGNC Symbol)

Synonyms

KCNMB2, KCNMBL

Description

potassium large conductance calcium-activated channel, subfamily M beta member 3 (HGNC Symbol)

Entrez gene summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]

Chromosome

3 (Chromosome progress)

Cytoband

q26.32

Chromosome location (bp)

178957530 - 178984790

Ensembl

ENSG00000171121 (version 73.37)

Entrez gene

27094

UniProt

Q9NPA1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPA1

Antibodypedia

KCNMB3 antibodies
 

PROTEIN VIEW

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KCNMB3-001
 
KCNMB3-002
 
KCNMB3-003
 
KCNMB3-004
 
KCNMB3-005
 
KCNMB3-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNMB3-001 ENSP00000418536
ENST00000485523
Q9NPA1
Show all »
Show » Show » 257 29 No 2
KCNMB3-002 ENSP00000417091
ENST00000497599
Q9NPA1
Show all »
Show » Show » 173 19.5 No 1
KCNMB3-003 ENSP00000376452
ENST00000392686
Q9NPA1
Show all »
Show » Show » 257 29 No 2
KCNMB3-004 ENSP00000319370
ENST00000314235
Q9NPA1
Show all »
Show » Show » 279 31.6 No 2
KCNMB3-005 ENSP00000376451
ENST00000392685
Q9NPA1
Show all »
Show » Show » 275 31.1 No 2
KCNMB3-007 ENSP00000327866
ENST00000349697
Q9NPA1
Show all »
Show » Show » 277 31.4 No 2