ATP6V0E2

GENE INFORMATION

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Gene name

ATP6V0E2 (HGNC Symbol)

Synonyms

ATP6V0E2L, C7orf32

Description

ATPase, H+ transporting V0 subunit e2 (HGNC Symbol)

Entrez gene summary

Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component (Blake-Palmer et al., 2007 [PubMed 17350184]).[supplied by OMIM, Mar 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q36.1

Chromosome location (bp)

149570057 - 149577784

Ensembl

ENSG00000171130 (version 73.37)

Entrez gene

155066

UniProt

Q8NHE4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NHE4

Antibodypedia

ATP6V0E2 antibodies
 

PROTEIN VIEW

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ATP6V0E2-001
 
ATP6V0E2-002
 
ATP6V0E2-003
 
ATP6V0E2-004
 
ATP6V0E2-005
 
ATP6V0E2-007
 
ATP6V0E2-010
 
ATP6V0E2-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V0E2-001 ENSP00000411672
ENST00000421974
E9PAS2
Show all »
Show » Show » 213 22 Yes 2
ATP6V0E2-002 ENSP00000410220
ENST00000456496
Q8NHE4
Show all »
Show » Show » 130 14.3 Yes 2
ATP6V0E2-003 ENSP00000417939
ENST00000479613
Q8NHE4
Show all »
Show » Show » 187 19.5 No 2
ATP6V0E2-004 ENSP00000420679
ENST00000471877
Q8NHE4
Show all »
Show » Show » 81 9.2 No 2
ATP6V0E2-005 ENSP00000420012
ENST00000464683
F8WDM2
Show all »
Show » Show » 79 8.9 No 2
ATP6V0E2-007 ENSP00000475645
ENST00000464662
Show » Show » 81 9.2 No 2
ATP6V0E2-010 ENSP00000396148
ENST00000425642
Q8NHE4
Show all »
Show » Show » 81 9.2 No 2
ATP6V0E2-011 ENSP00000475904
ENST00000606024
Show » Show » 164 16.9 No 2