KCND3

GENE INFORMATION

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Gene name

KCND3 (HGNC Symbol)

Synonyms

KSHIVB, Kv4.3

Description

potassium voltage-gated channel, Shal-related subfamily, member 3 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

112313284 - 112531777

Ensembl

ENSG00000171385 (version 73.37)

Entrez gene

3752

UniProt

Q9UK17 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UK17

Antibodypedia

KCND3 antibodies
 

PROTEIN VIEW

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KCND3-001
 
KCND3-002
 
KCND3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCND3-001 ENSP00000319591
ENST00000315987
Q9UK17
Show all »
Show » Show » 655 73.5 Yes 6
KCND3-002 ENSP00000358711
ENST00000369697
Q9UK17
Show all »
Show » Show » 636 71.4 Yes 6
KCND3-201 ENSP00000306923
ENST00000302127
Q9UK17
Show all »
Show » Show » 636 71.4 Yes 6