APLN

GENE INFORMATION

? »

Gene name

APLN (HGNC Symbol)

Synonyms

apelin, XNPEP2

Description

Apelin (HGNC Symbol)

Entrez gene summary

This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.[provided by RefSeq, Feb 2010]

Chromosome

X

Cytoband

q26.1

Chromosome location (bp)

129645809 - 129654937

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000171388 (version 78.38)

Entrez gene

8862

UniProt

neXtProt

Antibodypedia

APLN antibodies
 

PROTEIN VIEW

? »
 
 
 
APLN-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APLN-001 ENSP00000391800
ENST00000429967
B2R550
Show all »
Show » 122 12.9 No 0