APLN

GENE INFORMATION

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Gene name

APLN (HGNC Symbol)

Synonyms

apelin, XNPEP2

Description

apelin (HGNC Symbol)

Entrez gene summary

This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.[provided by RefSeq, Feb 2010]

Chromosome

X (Chromosome progress)

Cytoband

q26.1

Chromosome location (bp)

128779240 - 128788933

Ensembl

ENSG00000171388 (version 73.37)

Entrez gene

8862

UniProt

Q9ULZ1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9ULZ1

Antibodypedia

APLN antibodies
 

PROTEIN VIEW

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APLN-001
 
APLN-201
 
APLN-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APLN-001 ENSP00000391800
ENST00000429967
B2R550
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122 12.9 No 0
APLN-201 ENSP00000305464
ENST00000307484
Q9ULZ1
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Show » Show » 77 8.6 Yes 0
APLN-202 ENSP00000390834
ENST00000427399
B2R550
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122 12.9 No 0