Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nucleus, Plasma membrane

Additional location(s)

Vesicles 

Staining summary

Localized to nucleus, plasma membrane and vesicles.

Reliability (APE)

Very low

Antibodies in assay

HPA039061, HPA039062
 

Antibody HPA039061

 

Antibody HPA039062

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Vesicles Nucleus, Plasma membrane 

Staining characteristics

  

Staining intensity

Strong Strong 

Validation

Location not consistent with experimental gene/protein characterization data.
 
Location not consistent with experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli Nucleus, Plasma membrane 

Staining characteristics

  

Staining intensity

Weak Moderate 

Validation

Location not consistent with experimental gene/protein characterization data.
 
Location not consistent with experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Vesicles Nucleus, Plasma membrane 

Staining characteristics

Speckle  

Staining intensity

Weak Moderate 

Validation

Location not consistent with experimental gene/protein characterization data.
 
Location not consistent with experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & vesicles.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus & plasma membrane.
 

Summary

Staining fo the nucleus in all three cell lines. Additional staining of vesicles in A-431 and U-251 MG.   Staining of nucleus and plasma membrane in all three cell lines.  

Validation

The subcellular location is not consistent with literature.
 
The subcellular location is not consistent with literature.
 

Dictionary

Nucleus
Plasma membrane
Endosome