QARS

GENE INFORMATION

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Gene name

QARS

Synonyms

Description

glutaminyl-tRNA synthetase (HGNC Symbol)

Entrez gene summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

3 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

49133365 - 49142553

Ensembl

ENSG00000172053 (version 73.37)

Entrez gene

5859

UniProt

P47897 (UniProt - Evidence at protein level)

neXtProt

NX_P47897

Antibodypedia

QARS antibodies
 

PROTEIN VIEW

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QARS-001
 
QARS-003
 
QARS-005
 
QARS-009
 
QARS-023
 
QARS-026
 
QARS-027
 
QARS-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

QARS-001 ENSP00000307567
ENST00000306125
P47897
Show all »
Show » Show » 775 87.8 No 0
QARS-003 ENSP00000389823
ENST00000430182
F2Z2V6
Show all »
Show » 100 10.7 No 0
QARS-005 ENSP00000390015
ENST00000414533
B4DWJ2
Show all »
Show » 764 86.6 No 0
QARS-009 ENSP00000396326
ENST00000453392
H7C0R3
Show all »
Show » 253 28.6 No 0
QARS-023 ENSP00000392850
ENST00000452739
C9J165
Show all »
Show » Show » 305 34.3 No 0
QARS-026 ENSP00000415247
ENST00000418549
F2Z2V6
Show all »
Show » 100 10.7 No 0
QARS-027 ENSP00000414686
ENST00000417025
C9JSG9
Show all »
Show » 182 20.1 No 0
QARS-201 ENSP00000399119
ENST00000420147
B7Z840
Show all »
Show » 282 31.6 Yes 0