CXCR6

GENERAL INFORMATION

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Gene name

CXCR6

Gene description

Chemokine (C-X-C motif) receptor 6

Protein class

CD markers
G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

Protein localization

Gastrointestinal tract, hepatocytes, renal tubules, urothelium, decidua, macrophages in lung, Leydig cells and Purkinje cells exhibited weak to moderate cytoplasmic positivity. Other normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA047591
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CXCR6 (HGNC Symbol)

Synonyms

BONZO, CD186, STRL33, TYMSTR

Description

Chemokine (C-X-C motif) receptor 6 (HGNC Symbol)

Entrez gene summary

Chromosome

3

Cytoband

p21.31

Chromosome location (bp)

45940933 - 45948353

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172215 (version 78.38)

Entrez gene

10663

UniProt

O00574 (UniProt - Evidence at transcript level)

neXtProt

NX_O00574

Antibodypedia

CXCR6 antibodies


PROTEIN BROWSER

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ENST00000304552
 
ENST00000438735
 
ENST00000457814
 
ENST00000458629
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CXCR6-001 ENSP00000304414
ENST00000304552
O00574
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Show » Show » 342 39.3 No 7
CXCR6-002 ENSP00000396218
ENST00000438735
O00574
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Show » Show » 342 39.3 No 7
CXCR6-003 ENSP00000396886
ENST00000457814
O00574
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Show » Show » 342 39.3 No 7
CXCR6-004 ENSP00000395704
ENST00000458629
O00574
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Show » Show » 342 39.3 No 7