CEBPB

GENE INFORMATION

? »

Gene name

CEBPB (HGNC Symbol)

Synonyms

C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5

Description

CCAAT/enhancer binding protein (C/EBP), beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.13

Chromosome location (bp)

48807376 - 48809212

Ensembl

ENSG00000172216 (version 73.37)

Entrez gene

1051

UniProt

P17676 (UniProt - Evidence at protein level)

neXtProt

NX_P17676

Antibodypedia

CEBPB antibodies
 

PROTEIN VIEW

? »
 
 
 
CEBPB-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEBPB-001 ENSP00000305422
ENST00000303004
P17676
Show all »
Show » Show » 345 36.1 No 0