AZU1

GENE INFORMATION

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Gene name

AZU1 (HGNC Symbol)

Synonyms

AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC

Description

Azurocidin 1 (HGNC Symbol)

Entrez gene summary

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

825097 - 832017

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172232 (version 75.37)

Entrez gene

566

UniProt

P20160 (UniProt - Evidence at protein level)

neXtProt

NX_P20160

Antibodypedia

AZU1 antibodies
 

PROTEIN VIEW

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AZU1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AZU1-001 ENSP00000233997
ENST00000233997
P20160
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