ARNT2

GENE INFORMATION

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Gene name

ARNT2 (HGNC Symbol)

Synonyms

bHLHe1, KIAA0307

Description

aryl-hydrocarbon receptor nuclear translocator 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

80696692 - 80890278

Ensembl

ENSG00000172379 (version 73.37)

Entrez gene

9915

UniProt

Q9HBZ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HBZ2

Antibodypedia

ARNT2 antibodies
 

PROTEIN VIEW

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ARNT2-001
 
ARNT2-004
 
ARNT2-006
 
ARNT2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARNT2-001 ENSP00000307479
ENST00000303329
Q9HBZ2
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Show » Show » 717 78.7 No 0
ARNT2-004 ENSP00000453792
ENST00000527771
Q9HBZ2
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Show » Show » 706 77.6 No 0
ARNT2-006 ENSP00000453651
ENST00000533983
Q9HBZ2
Show all »
Show » Show » 706 77.6 No 0
ARNT2-007 ENSP00000452961
ENST00000525103
H0YKW1
Show all »
Show » Show » 130 14.4 No 0