HCFC1

GENE INFORMATION

? »

Gene name

HCFC1 (HGNC Symbol)

Synonyms

CFF, HCF-1, HCF1, HFC1, MGC70925, VCAF

Description

host cell factor C1 (VP16-accessory protein) (HGNC Symbol)

Entrez gene summary

This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

q28

Chromosome location (bp)

153213004 - 153237258

Ensembl

ENSG00000172534 (version 73.37)

Entrez gene

3054

UniProt

P51610 (UniProt - Evidence at protein level)

neXtProt

NX_P51610

Antibodypedia

HCFC1 antibodies
 

PROTEIN VIEW

? »
 
 
 
HCFC1-001
 
HCFC1-003
 
HCFC1-004
 
HCFC1-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HCFC1-001 ENSP00000309555
ENST00000310441
P51610
Show all »
Show » Show » 2035 208.7 No 0
HCFC1-003 ENSP00000359001
ENST00000369984
A6NEM2
Show all »
Show » Show » 2080 213.5 No 0
HCFC1-004 ENSP00000399589
ENST00000444191
Show » 611 63.1 No 0
HCFC1-201 ENSP00000346174
ENST00000354233
P51610
Show all »
Show » Show » 1966 201.8 No 0