HPSE2

GENE INFORMATION

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Gene name

HPSE2 (HGNC Symbol)

Synonyms

HPA2, HPR2, UFS

Description

Heparanase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Chromosome

10

Cytoband

q24.2

Chromosome location (bp)

100218875 - 100995619

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172987 (version 75.37)

Entrez gene

60495

UniProt

Q8WWQ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WWQ2

Antibodypedia

HPSE2 antibodies
 

PROTEIN VIEW

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HPSE2-001
 
HPSE2-002
 
HPSE2-003
 
HPSE2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HPSE2-001 ENSP00000359583
ENST00000370552
Q8WWQ2
Show all »
Show » Show » 592 66.6 Yes 0
HPSE2-002 ENSP00000359577
ENST00000370546
Q8WWQ2
Show all »
Show » Show » 548 61.8 Yes 0
HPSE2-003 ENSP00000359580
ENST00000370549
Q8WWQ2
Show all »
Show » Show » 534 60.1 Yes 0
HPSE2-201 ENSP00000384384
ENST00000404542
Q8WWQ2
Show all »
Show » Show » 480 53.9 Yes 0