ADCY5

GENE INFORMATION

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Gene name

ADCY5 (HGNC Symbol)

Synonyms

AC5

Description

adenylate cyclase 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Chromosome

3 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

123001143 - 123168605

Ensembl

ENSG00000173175 (version 73.37)

Entrez gene

111

UniProt

O95622 (UniProt - Evidence at protein level)

neXtProt

NX_O95622

Antibodypedia

ADCY5 antibodies
 

PROTEIN VIEW

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ADCY5-001
 
ADCY5-002
 
ADCY5-003
 
ADCY5-004
 
ADCY5-005
 
ADCY5-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADCY5-001 ENSP00000419361
ENST00000462833
O95622
Show all »
Show » Show » 1261 138.9 No >9
ADCY5-002 ENSP00000418537
ENST00000491190
B3KWA8
Show all »
Show » Show » 919 103.9 No 7
ADCY5-003 ENSP00000308685
ENST00000309879
O95622
Show all »
Show » Show » 911 102.6 No 7
ADCY5-004 ENSP00000420082
ENST00000466617
C9JRT8
Show all »
Show » Show » 492 55.5 No 4
ADCY5-005 ENSP00000420252
ENST00000483566
C9JQ38
Show all »
Show » 90 10.3 No 0
ADCY5-007 ENSP00000417789
ENST00000476455
F8WBM0
Show all »
78 8.8 No 0