C1QA

GENE INFORMATION

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Gene name

C1QA

Synonyms

Description

Complement component 1, q subcomponent, A chain (HGNC Symbol)

Entrez gene summary

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.12

Chromosome location (bp)

22962999 - 22966101

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173372 (version 75.37)

Entrez gene

712

UniProt

P02745 (UniProt - Evidence at protein level)

neXtProt

NX_P02745

Antibodypedia

C1QA antibodies
 

PROTEIN VIEW

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C1QA-001
 
C1QA-002
 
C1QA-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C1QA-001 ENSP00000363773
ENST00000374642
P02745
Show all »
Show » Show » 245 26 Yes 0
C1QA-002 ENSP00000416841
ENST00000438241
Show » Show » 221 23.4 Yes 0
C1QA-003 ENSP00000385564
ENST00000402322
P02745
Show all »
Show » Show » 245 26 Yes 0