XCR1

GENE INFORMATION

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Gene name

XCR1 (HGNC Symbol)

Synonyms

CCXCR1, GPR5

Description

chemokine (C motif) receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

46058516 - 46069234

Ensembl

ENSG00000173578 (version 73.37)

Entrez gene

2829

UniProt

P46094 (UniProt - Evidence at protein level)

neXtProt

NX_P46094

Antibodypedia

XCR1 antibodies
 

PROTEIN VIEW

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XCR1-001
 
XCR1-002
 
XCR1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

XCR1-001 ENSP00000310405
ENST00000309285
P46094
Show all »
Show » Show » 333 38.5 No 7
XCR1-002 ENSP00000379277
ENST00000395946
Q689E2
Show all »
Show » 36 4.1 No 0
XCR1-201 ENSP00000438119
ENST00000542109
P46094
Show all »
Show » Show » 333 38.5 No 7