CCR9

GENE INFORMATION

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Gene name

CCR9 (HGNC Symbol)

Synonyms

CDw199, GPR-9-6, GPR28

Description

chemokine (C-C motif) receptor 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

3 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

45927996 - 45944667

Ensembl

ENSG00000173585 (version 73.37)

Entrez gene

10803

UniProt

P51686 (UniProt - Evidence at protein level)

neXtProt

NX_P51686

Antibodypedia

CCR9 antibodies
 

PROTEIN VIEW

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CCR9-001
 
CCR9-002
 
CCR9-003
 
CCR9-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCR9-001 ENSP00000350256
ENST00000357632
P51686
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Show » Show » 369 42 No 7
CCR9-002 ENSP00000379292
ENST00000395963
P51686
Show all »
Show » Show » 357 40.7 No 7
CCR9-003 ENSP00000393267
ENST00000422395
C9JWC0
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107 11.4 No 0
CCR9-201 ENSP00000348260
ENST00000355983
P51686
Show all »
Show » Show » 357 40.7 No 7