KCNH6

GENE INFORMATION

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Gene name

KCNH6 (HGNC Symbol)

Synonyms

erg2, HERG2, Kv11.2

Description

potassium voltage-gated channel, subfamily H (eag-related), member 6 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Chromosome

17 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

61600695 - 61626338

Ensembl

ENSG00000173826 (version 73.37)

Entrez gene

81033

UniProt

Q9H252 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H252

Antibodypedia

KCNH6 antibodies
 

PROTEIN VIEW

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KCNH6-001
 
KCNH6-002
 
KCNH6-003
 
KCNH6-004
 
KCNH6-005
 
KCNH6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNH6-001 ENSP00000318212
ENST00000314672
J9JID4
Show all »
Show » Show » 958 106.4 No 6
KCNH6-002 ENSP00000463830
ENST00000581784
Q9H252
Show all »
Show » Show » 905 100.4 No 5
KCNH6-003 ENSP00000464672
ENST00000580652
Q9H252
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Show » Show » 502 56.3 No 4
KCNH6-004 ENSP00000462417
ENST00000583465
J3KSC2
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65 7.4 No 0
KCNH6-005 ENSP00000463533
ENST00000583023
Q9H252
Show all »
Show » Show » 994 109.9 No 5
KCNH6-201 ENSP00000396900
ENST00000456941
Q9H252
Show all »
Show » Show » 905 100.4 No 5