SELP

GENE INFORMATION

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Gene name

SELP (HGNC Symbol)

Synonyms

CD62, CD62P, GMP140, GRMP, PADGEM, PSEL

Description

selectin P (granule membrane protein 140kDa, antigen CD62) (HGNC Symbol)

Entrez gene summary

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q24.2

Chromosome location (bp)

169558087 - 169599431

Ensembl

ENSG00000174175 (version 73.37)

Entrez gene

6403

UniProt

P16109 (UniProt - Evidence at protein level)

neXtProt

NX_P16109

Antibodypedia

SELP antibodies
 

PROTEIN VIEW

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SELP-001
 
SELP-002
 
SELP-004
 
SELP-005
 
SELP-006
 
SELP-008
 
SELP-201
 
SELP-202
 
SELP-203
 
SELP-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SELP-001 ENSP00000263686
ENST00000263686
P16109
Show all »
Show » Show » 830 90.8 No 1
SELP-002 ENSP00000391694
ENST00000426706
Q5R349
Show all »
Show » Show » 789 86.5 No 0
SELP-004 ENSP00000399368
ENST00000458599
Q5R342
Show all »
Show » Show » 646 70.9 No 1
SELP-005 ENSP00000356760
ENST00000367786
Q5R341
Show all »
Show » Show » 768 84 No 1
SELP-006 ENSP00000356762
ENST00000367788
Q5R345
Show all »
Show » Show » 768 84.3 No 1
SELP-008 ENSP00000356769
ENST00000367795
F6VVT6
Show all »
Show » Show » 444 49.6 No 0
SELP-201 ENSP00000356765
ENST00000367791
Q5R343
Show all »
Show » Show » 644 70.7 No 1
SELP-202 ENSP00000356766
ENST00000367792
Q5R342
Show all »
Show » Show » 646 70.9 No 1
SELP-203 ENSP00000356767
ENST00000367793
Q5R345
Show all »
Show » Show » 768 84.3 No 1
SELP-204 ENSP00000356768
ENST00000367794
Q5R341
Show all »
Show » Show » 768 84 No 1