EVX2

GENERAL INFORMATION

? »

Gene name

EVX2

Gene description

Even-skipped homeobox 2

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Group enriched (colon, prostate, rectum, testis)
GTEx:Tissue enhanced (cervix, uterine, testis)

Protein evidence

Evidence at transcript level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA041576
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Group enriched (colon, prostate, rectum, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cervix, uterine, testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

EVX2

Synonyms

Description

Even-skipped homeobox 2 (HGNC Symbol)

Entrez gene summary

This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

176077472 - 176083913

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000174279 (version 78.38)

Entrez gene

344191

UniProt

Q03828 (UniProt - Evidence at transcript level)

neXtProt

NX_Q03828

Antibodypedia

EVX2 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000308618
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EVX2-001 ENSP00000312385
ENST00000308618
Q03828
Show all »
Show » Show » 476 47.8 No 0