MRPL11

GENE INFORMATION

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Gene name

MRPL11

Synonyms

Description

Mitochondrial ribosomal protein L11 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.2

Chromosome location (bp)

66202546 - 66234209

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174547 (version 75.37)

Entrez gene

65003

UniProt

Q9Y3B7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3B7

Antibodypedia

MRPL11 antibodies
 

PROTEIN VIEW

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MRPL11-001
 
MRPL11-002
 
MRPL11-004
 
MRPL11-005
 
MRPL11-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL11-001 ENSP00000308897
ENST00000310999
Q9Y3B7
Show all »
Show » Show » 192 20.7 No 0
MRPL11-002 ENSP00000415356
ENST00000430466
Q9Y3B7
Show all »
Show » Show » 166 18.2 No 0
MRPL11-004 ENSP00000436904
ENST00000534488
E9PQB6
Show all »
Show » Show » 75 8.1 No 0
MRPL11-005 ENSP00000431405
ENST00000528272
H0YCD5
Show all »
Show » Show » 63 6.8 No 0
MRPL11-006 ENSP00000329630
ENST00000329819
Q9Y3B7
Show all »
Show » Show » 181 19.5 No 0