KLK15

GENE INFORMATION

? »

Gene name

KLK15 (HGNC Symbol)

Synonyms

ACO, HSRNASPH, prostinogen

Description

kallikrein-related peptidase 15 (HGNC Symbol)

Entrez gene summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

51328545 - 51340469

Ensembl

ENSG00000174562 (version 73.37)

Entrez gene

55554

UniProt

Q9H2R5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H2R5

Antibodypedia

KLK15 antibodies
 

PROTEIN VIEW

? »
 
 
 
KLK15-001
 
KLK15-002
 
KLK15-003
 
KLK15-004
 
KLK15-008
 
KLK15-201
 
KLK15-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK15-001 ENSP00000314783
ENST00000326856
Q6ISI0
Show all »
Show » 255 28 Yes 0
KLK15-002 ENSP00000471164
ENST00000596931
M0R0D7
Show all »
Show » 160 17.9 Yes 0
KLK15-003 ENSP00000469315
ENST00000598239
Q9H2R5
Show all »
Show » Show » 256 28.1 Yes 0
KLK15-004 ENSP00000468856
ENST00000602114
M0QX22
Show all »
Show » Show » 120 13.8 Yes 0
KLK15-008 ENSP00000472523
ENST00000598673
M0R2F7
Show all »
Show » 43 5.2 No 0
KLK15-201 ENSP00000301421
ENST00000301421
Q9H2R5
Show all »
Show » Show » 161 18 Yes 0
KLK15-202 ENSP00000415136
ENST00000416184
Q9H2R5
Show all »
Show » Show » 171 19.3 Yes 0