PTDSS2

GENE INFORMATION

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Gene name

PTDSS2 (HGNC Symbol)

Synonyms

PSS2

Description

phosphatidylserine synthase 2 (HGNC Symbol)

Entrez gene summary

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009]

Chromosome

11 (Chromosome progress)

Cytoband

p15.5

Chromosome location (bp)

448268 - 491393

Ensembl

ENSG00000174915 (version 73.37)

Entrez gene

81490

UniProt

Q9BVG9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BVG9

Antibodypedia

PTDSS2 antibodies
 

PROTEIN VIEW

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PTDSS2-001
 
PTDSS2-005
 
PTDSS2-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTDSS2-001 ENSP00000308258
ENST00000308020
Q9BVG9
Show all »
Show » Show » 487 56.3 No 9
PTDSS2-005 ENSP00000435168
ENST00000531520
E9PLE4
Show all »
Show » 81 8.6 No 0
PTDSS2-012 ENSP00000432100
ENST00000527479
E9PS47
Show all »
Show » 60 6.3 No 0