SMAD2

TISSUE ATLAS

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Gene description

SMAD family member 2

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression level in 69 of 82 analyzed normal tissue cell types.

Protein expression

Most normal tissues displayed moderate nuclear positivity. Strong nuclear staining was observed in decidual cells, breast, most cells in CNS and male genitalia. Hepatocytes and lymphoid tissues were weakly stained.

Protein class

Candidate cancer biomarkers, Potential transmembrane proteins, Transcription factors

Protein evidence

Medium

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Skeletal muscle
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB025507