DPP10

GENE INFORMATION

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Gene name

DPP10 (HGNC Symbol)

Synonyms

DPRP3

Description

dipeptidyl-peptidase 10 (non-functional) (HGNC Symbol)

Entrez gene summary

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q14.1

Chromosome location (bp)

115199876 - 116603328

Ensembl

ENSG00000175497 (version 73.37)

Entrez gene

57628

UniProt

Q8N608 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N608

Antibodypedia

DPP10 antibodies
 

PROTEIN VIEW

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DPP10-001
 
DPP10-002
 
DPP10-004
 
DPP10-005
 
DPP10-007
 
DPP10-008
 
DPP10-009
 
DPP10-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DPP10-001 ENSP00000386565
ENST00000410059
Q8N608
Show all »
Show » Show » 796 90.9 No 1
DPP10-002 ENSP00000387038
ENST00000409163
Q8N608
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Show » Show » 746 85.5 No 0
DPP10-004 ENSP00000408535
ENST00000429914
F8WEB2
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60 6.9 No 0
DPP10-005 ENSP00000309066
ENST00000310323
Q8N608
Show all »
Show » Show » 789 90.1 No 1
DPP10-007 ENSP00000376855
ENST00000393147
Q8N608
Show all »
Show » Show » 800 91.1 No 1
DPP10-008 ENSP00000391092
ENST00000436732
C9J4M8
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60 7 No 0
DPP10-009 ENSP00000376854
ENST00000393146
J3KPP1
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Show » Show » 259 29.6 No 1
DPP10-011 ENSP00000402499
ENST00000419287
J3KQK8
Show all »
97 11.1 No 0