P2RY2

GENE INFORMATION

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Gene name

P2RY2 (HGNC Symbol)

Synonyms

P2U

Description

purinergic receptor P2Y, G-protein coupled, 2 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]

Chromosome

11 (Chromosome progress)

Cytoband

q13.4

Chromosome location (bp)

72929343 - 72947397

Ensembl

ENSG00000175591 (version 73.37)

Entrez gene

5029

UniProt

P41231 (UniProt - Evidence at protein level)

neXtProt

NX_P41231

Antibodypedia

P2RY2 antibodies
 

PROTEIN VIEW

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P2RY2-001
 
P2RY2-002
 
P2RY2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

P2RY2-001 ENSP00000310305
ENST00000311131
P41231
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Show » Show » 377 42.3 No 7
P2RY2-002 ENSP00000377222
ENST00000393597
P41231
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Show » Show » 377 42.3 No 7
P2RY2-003 ENSP00000377221
ENST00000393596
P41231
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Show » Show » 377 42.3 No 7