BNIP3

GENE INFORMATION

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Gene name

BNIP3 (HGNC Symbol)

Synonyms

Nip3

Description

BCL2/adenovirus E1B 19kDa interacting protein 3 (HGNC Symbol)

Entrez gene summary

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq, Mar 2011]

Chromosome

10 (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

133781578 - 133795435

Ensembl

ENSG00000176171 (version 73.37)

Entrez gene

664

UniProt

Q12983 (UniProt - Evidence at protein level)

neXtProt

NX_Q12983

Antibodypedia

BNIP3 antibodies
 

PROTEIN VIEW

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BNIP3-001
 
BNIP3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BNIP3-001 ENSP00000357625
ENST00000368636
Q12983
Show all »
Show » Show » 194 21.5 No 1
BNIP3-201 ENSP00000446145
ENST00000540159
B4DHJ7
Show all »
Show » Show » 180 19.9 No 0