IRX5

GENE INFORMATION

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Gene name

IRX5 (HGNC Symbol)

Synonyms

IRX-2a

Description

iroquois homeobox 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Chromosome

16 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

54964774 - 54968397

Ensembl

ENSG00000176842 (version 73.37)

Entrez gene

10265

UniProt

P78411 (UniProt - Evidence at protein level)

neXtProt

NX_P78411

Antibodypedia

IRX5 antibodies
 

PROTEIN VIEW

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IRX5-001
 
IRX5-002
 
IRX5-003
 
IRX5-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IRX5-001 ENSP00000378132
ENST00000394636
P78411
Show all »
Show » Show » 483 50.4 No 0
IRX5-002 ENSP00000316250
ENST00000320990
P78411
Show all »
Show » Show » 482 50.3 No 0
IRX5-003 ENSP00000453660
ENST00000560154
H0YML8
Show all »
263 27.2 No 0
IRX5-004 ENSP00000453725
ENST00000558597
P78411
Show all »
Show » Show » 417 43.7 No 0