ACER2

GENE INFORMATION

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Gene name

ACER2 (HGNC Symbol)

Synonyms

ASAH3L, FLJ41587

Description

alkaline ceramidase 2 (HGNC Symbol)

Entrez gene summary

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]

Chromosome

9 (Chromosome progress)

Cytoband

p22.1

Chromosome location (bp)

19408925 - 19452018

Ensembl

ENSG00000177076 (version 73.37)

Entrez gene

340485

UniProt

Q5QJU3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5QJU3

Antibodypedia

ACER2 antibodies
 

PROTEIN VIEW

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ACER2-001
 
ACER2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACER2-001 ENSP00000342609
ENST00000340967
Q5QJU3
Show all »
Show » Show » 275 31.3 No 7
ACER2-201 ENSP00000369735
ENST00000380376
Q5QJU3
Show all »
Show » Show » 140 15.9 No 4