ANO6

GENE INFORMATION

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Gene name

ANO6 (HGNC Symbol)

Synonyms

DKFZp313M0720, TMEM16F

Description

anoctamin 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

Chromosome

12 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

45609770 - 45834187

Ensembl

ENSG00000177119 (version 73.37)

Entrez gene

196527

UniProt

Q4KMQ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q4KMQ2

Antibodypedia

ANO6 antibodies
 

PROTEIN VIEW

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ANO6-001
 
ANO6-002
 
ANO6-003
 
ANO6-004
 
ANO6-005
 
ANO6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANO6-001 ENSP00000320087
ENST00000320560
Q4KMQ2
Show all »
Show » Show » 910 106.2 No 9
ANO6-002 ENSP00000391417
ENST00000425752
Q4KMQ2
Show all »
Show » Show » 929 108.1 No >9
ANO6-003 ENSP00000413137
ENST00000441606
Q4KMQ2
Show all »
Show » Show » 892 104 No 9
ANO6-004 ENSP00000449423
ENST00000550630
F8VX71
Show all »
45 5 No 0
ANO6-005 ENSP00000409126
ENST00000423947
Q4KMQ2
Show all »
Show » Show » 931 108.4 No 9
ANO6-201 ENSP00000413840
ENST00000435642
Q4KMQ2
Show all »
Show » Show » 929 108.1 No >9