RPS6KA3

GENE INFORMATION

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Gene name

RPS6KA3 (HGNC Symbol)

Synonyms

CLS, HU-3, MRX19, RSK, RSK2

Description

ribosomal protein S6 kinase, 90kDa, polypeptide 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

p22.12

Chromosome location (bp)

20168029 - 20285523

Ensembl

ENSG00000177189 (version 73.37)

Entrez gene

6197

UniProt

P51812 (UniProt - Evidence at protein level)

neXtProt

NX_P51812

Antibodypedia

RPS6KA3 antibodies
 

PROTEIN VIEW

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RPS6KA3-001
 
RPS6KA3-002
 
RPS6KA3-003
 
RPS6KA3-201
 
RPS6KA3-202
 
RPS6KA3-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPS6KA3-001 ENSP00000368884
ENST00000379565
P51812
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Show » Show » 740 83.7 No 0
RPS6KA3-002 ENSP00000407655
ENST00000457145
B1AXG1
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Show » 227 26.2 No 0
RPS6KA3-003 ENSP00000388512
ENST00000438357
B1AXG2
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Show » 133 15.3 No 0
RPS6KA3-201 ENSP00000368865
ENST00000379548
F5GYC4
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Show » Show » 710 80.6 No 0
RPS6KA3-202 ENSP00000444837
ENST00000540702
B4DG22
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Show » Show » 711 80.6 No 0
RPS6KA3-203 ENSP00000440220
ENST00000544447
B7ZB17
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Show » Show » 712 80.7 No 0